Figure 5

Absorption of 59Fe- or 51Cr-labeled SPIOs in mice. (A) 59Fe-labeled polymer-coated SPIOs or so-called “nanosomes” (oleic acid-stabilized, hydrophobic SPIOs embedded in chylomicron-like lipid micelles) [29] were administered by gavage to groups of mice (n = 4–5). The 59Fe-WBR was measured after 1–14 d. (B) The same procedure as with 51Cr-labeled SPIOs, “nanosomes” and 51CrCl3 (n = 8). Values of the respective 51Cr-WBR for each individual mouse is given at day 7 day (which is taken as the apparent gastrointestinal 51Cr absorption).

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