Figure 5:

(A) The nanorattle-based DNA detection method using sandwich hybridization of (1) magnetic bead that are loaded with capture probes, (2) target sequence, and (3) ultrabright SERS nanorattles that are loaded with reporter probes. (B) A magnet is applied to concentrate the hybridization sandwiches at a detection spot for SERS measurements. Reprinted with permission from [27]. Copyright 2016 Elsevier.

© De Gruyter