Metal-enhanced fluorescence on different nano-array structures.
(A) Scanning probe microscopy images of 1D and 2D gratings after metal deposition. Grating pitch=400 nm. (B) Enhancement factor (EF) of the fluorescence intensity on different substrates using plane glass as reference (EF=1.0) (A and B adapted from Ref.  with permission from John Wiley and Sons). (C) Schematic (overview and cross section) of disk-coupled dots-on-pillar antenna array (D2PA) plate without an immunoassay. D2PA has an array of dense three-dimensional (3D) resonant cavity nano-antennas (formed by the gold disks on top of periodic nonmetallic pillars and the gold backplane on the pillar foot) with dense plasmonic nanodots inside and couples the metallic components through nanogaps. (D) Measured area average fluorescence intensity spectrum of the human-IgG labeled with IRDye800CW captured by the assay on the D2PA (red line) and the glass plate (blue line, which is amplified 1000 times to be visible at given scales), respectively. (C and D reprinted with permission from ; copyright (2012) American Chemical Society). (E) SEM images of Au nanostructure with 5s oxygen plasma etching. (F) Fluorescence spectra intensity change with etching time (E and F reproduced from Ref.  with permission from The Royal Society of Chemistry).