Figure 3:

Optical imaging based on inherent nonlinearity of plasmonic nanostructures.

(A) SHG map of individual (A1) silver nanoparticles deposited on a coated substrate. Reprinted with permission from ref [124] and (A2) gold nanoparticles dispersed in gelatin. Reprinted with permission from ref [32]. (B) THG images of (B1) individual gold nanoparticles. Reprinted with permission from ref [36], and (B2) 5 nm silver colloids. Reprinted with permission from ref [35]. The very bright dots in (B1) correspond to 100 nm particles, and the rest are 40 nm particles. (C) Nonlinear PL images in tissues. (C1) Three-dimensional 2PL mapping of gold nanoshells in tumor, with field of view of 124 μm in all three dimensions. Reprinted with permission from ref [125]. (C2) Three-dimensional reconstructed intravital 3PL images of gold nanorod stained mouse brain blood vessels. Reprinted with permission from ref [126]. (D) Two photon microscopy of Karpas-299 cells labeled with gold nanoparticles and H258 dye at the membrane and the nuclear region respectively. The contrasts are based on (D1) intensity, and (D2) fluorescence lifetime. In (D2), the gold nanoparticles (yellow) are clearly distinguishable from the dye (blue-green color) Reprinted with permission from ref [127]. (E) Near-field fluorescence imaging with a gold nano dimer as localized FWM photon source. (E1) Topographic image of monodispersed red fluorescent microspheres. The double-lobed feature is due to the dimer antenna. (E2) Simultaneous near-field fluorescence image. Reprinted with permission from ref [128]. (F) Hyperspectral NSOM mapping the nanotriangles, based on (F1) 2PL and (F2) SHG, respectively. Reprinted with permission from ref [129].

© De Gruyter