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Supplementary Materials

QUANTIFICATION AND LOCALIZATION OF EXTENDED NANOPARTICLE DISTRIBUTIONS IN TISSUE USING MULTIPOLE EXPANSION

DOI: https://doi.org/10.1515/nano.0007.00030

QUANTIFICATION AND LOCALIZATION OF EXTENDED NANOPARTICLE DISTRIBUTIONS IN TISSUE USING MULTIPOLE EXPANSION

1 2 / U. Steinhoff 1 / M. Bär 1 / L. Trahms 1 / W. Haberkorn 1

1Physikalisch-Technische Bundesanstalt, Deutschland

2 frank.wiekhorst@ptb.de

Cite as: F. Wiekhorsts, U. Steinhoff, M. Bär, L. Trahms. QUANTIFICATION AND LOCALIZATION OF EXTENDED NANOPARTICLE DISTRIBUTIONS IN TISSUE USING MULTIPOLE EXPANSION, nano Online. (2016). DOI: https://doi.org/10.1515/nano.0007.00030

Cite as: F. Wiekhorsts, U. Steinhoff, M. Bär, L. Trahms. QUANTIFICATION AND LOCALIZATION OF EXTENDED NANOPARTICLE DISTRIBUTIONS IN TISSUE USING MULTIPOLE EXPANSION, Biomedical Engineering / Biomedizinische Technik. , (2013). DOI: https://doi.org/10.1515/bmt-2013-4345

Abstract

We present a multipole based approach to characterize arbitrarily distributed magnetic nanoparticle (MNP) accumulations in biological tissue. The derived analytical relations allow for the determination of the MNP total amount and centre of mass. Furthermore, it makes the discrimination between spatially extended and point like MNP accumulations possible. The results allow the quantitative assessment of magnetic drug targeting success by MNP specific magnetic measurement techniques.

Keywords: extended magnetic nanoparticle distribution; multipole moments; quantification; localization

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